LASP1 in Cellular Signaling and Gene Expression: More than Just a Cytoskeletal Regulator
LIM and SH3 protein 1 was originally identified as a structural cytoskeletal protein with scaffolding function.However, recent data suggest additional roles in cell signaling and gene expression, especially in tumor cells.These Tie Back novel functions are primarily regulated by the site-specific phosphorylation of LASP1.This review will focus on s